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Gene Expression Variability in Human Hepatic Drug Metabolizing Enzymes and Transporters

Interindividual variability in the expression of drug-metabolizing enzymes and transporters (DMETs) in human liver may contribute to interindividual differences in drug efficacy and adverse reactions. Published studies that analyzed variability in the expression of DMET genes were limited by sample...

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Detalles Bibliográficos
Autores principales: Yang, Lun, Price, Elvin T., Chang, Ching-Wei, Li, Yan, Huang, Ying, Guo, Li-Wu, Guo, Yongli, Kaput, Jim, Shi, Leming, Ning, Baitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634068/
https://www.ncbi.nlm.nih.gov/pubmed/23637747
http://dx.doi.org/10.1371/journal.pone.0060368