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Construction of a Single Lentiviral Vector Containing Tetracycline-Inducible Alb-uPA for Transduction of uPA Expression in Murine Hepatocytes

The SCID-beige/Alb-uPA mouse model is currently the best small animal model available for viral hepatitis infection studies [1]. But the construction procedure is often costly and time-consuming due to logistic and technical difficulties. Thus, the widespread application of these chimeric mice has b...

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Detalles Bibliográficos
Autores principales: Bai, Jiasi, Li, Jungang, Mao, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634076/
https://www.ncbi.nlm.nih.gov/pubmed/23626683
http://dx.doi.org/10.1371/journal.pone.0061412