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Insights into the molecular evolution of oxytocin receptor ligand binding

The design and development of selective ligands for the human OT (oxytocin) and AVP (arginine vasopressin) receptors is a big challenge since the different receptor subtypes and their native peptide ligands display great similarity. Detailed understanding of the mechanism of OT's interaction wi...

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Detalles Bibliográficos
Autores principales: Koehbach, Johannes, Stockner, Thomas, Bergmayr, Christian, Muttenthaler, Markus, Gruber, Christian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634130/
https://www.ncbi.nlm.nih.gov/pubmed/23356283
http://dx.doi.org/10.1042/BST20120256