Preclinical Activity of Simvastatin Induces Cell Cycle Arrest in G1 via Blockade of Cyclin D-Cdk4 Expression in Non-Small Cell Lung Cancer (NSCLC)

Lung cancer is the most common cause of cancer-related death. Nonetheless, a decrease in overall incidence and mortality has been observed in the last 30 years due to prevention strategies and improvements in the use of chemotherapeutic agents. In recent studies, Simvastatin (SIM) has demonstrated a...

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Detalles Bibliográficos
Autores principales: Liang, Yu-Wei, Chang, Chi-Chang, Hung, Chao-Ming, Chen, Tzu-Yu, Huang, Tzuu-Yuan, Hsu, Yi-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634414/
https://www.ncbi.nlm.nih.gov/pubmed/23481641
http://dx.doi.org/10.3390/ijms14035806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634414/
https://www.ncbi.nlm.nih.gov/pubmed/23481641
http://dx.doi.org/10.3390/ijms14035806

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