Cargando…

p53 and Ceramide as Collaborators in the Stress Response

The sphingolipid ceramide mediates various cellular processes in response to several extracellular stimuli. Some genotoxic stresses are able to induce p53-dependent ceramide accumulation leading to cell death. However, in other cases, in the absence of the tumor suppressor protein p53, apoptosis pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Hage-Sleiman, Rouba, Esmerian, Maria O., Kobeissy, Hadile, Dbaibo, Ghassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634419/
https://www.ncbi.nlm.nih.gov/pubmed/23455468
http://dx.doi.org/10.3390/ijms14034982