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Quick, Selective and Reversible Photocrosslinking Reaction between 5-Methylcytosine and 3-Cyanovinylcarbazole in DNA Double Strand

Selective photocrosslinking reaction between 3-cyanovinylcarbazole nucleoside ((CNV)K) and 5-methylcytosine ((m)C), which is known as epigenetic modification in genomic DNA, was developed. The reaction was completely finished within 5 s of 366 nm irradiation, and the rate of this photocrosslinking r...

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Detalles Bibliográficos
Autores principales: Fujimo, Kenzo, Konishi-Hiratsuka, Kaoru, Sakamoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634424/
https://www.ncbi.nlm.nih.gov/pubmed/23481638
http://dx.doi.org/10.3390/ijms14035765