Adsorption and Orientation of Human Islet Amyloid Polypeptide (hIAPP) Monomer at Anionic Lipid Bilayers: Implications for Membrane-Mediated Aggregation

Protein misfolding and aggregation cause serious degenerative diseases, such as Alzheimer’s and type II diabetes. Human islet amyloid polypeptide (hIAPP) is the major component of amyloid deposits found in the pancreas of type II diabetic patients. Increasing evidence suggests that β-cell death is r...

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Detalles Bibliográficos
Autores principales: Jia, Yan, Qian, Zhenyu, Zhang, Yun, Wei, Guanghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634446/
https://www.ncbi.nlm.nih.gov/pubmed/23519103
http://dx.doi.org/10.3390/ijms14036241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634446/
https://www.ncbi.nlm.nih.gov/pubmed/23519103
http://dx.doi.org/10.3390/ijms14036241

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