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Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease

The Amyloid-β (Aβ)-induced impairment of hippocampal synaptic plasticity is an underlying mechanism of memory loss in the early stages of Alzheimer’s disease (AD) in human and mouse models. The inhibition of the calcium/calmodulin-dependent protein kinase II (CaMKII) autophosphorylation plays an imp...

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Detalles Bibliográficos
Autores principales: Wang, Dong-Mei, Yang, Ya-Jun, Zhang, Li, Zhang, Xu, Guan, Fei-Fei, Zhang, Lian-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634479/
https://www.ncbi.nlm.nih.gov/pubmed/23478434
http://dx.doi.org/10.3390/ijms14035576