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Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease
The Amyloid-β (Aβ)-induced impairment of hippocampal synaptic plasticity is an underlying mechanism of memory loss in the early stages of Alzheimer’s disease (AD) in human and mouse models. The inhibition of the calcium/calmodulin-dependent protein kinase II (CaMKII) autophosphorylation plays an imp...
Autores principales: | Wang, Dong-Mei, Yang, Ya-Jun, Zhang, Li, Zhang, Xu, Guan, Fei-Fei, Zhang, Lian-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634479/ https://www.ncbi.nlm.nih.gov/pubmed/23478434 http://dx.doi.org/10.3390/ijms14035576 |
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