Global Gene Expression Profiling Reveals Functional Importance of Sirt2 in Endothelial Cells under Oxidative Stress

The NAD(+)-dependent deacetylases Sirt1 and Sirt2 mediate cellular stress responses and are highly expressed in vascular endothelial cells. In contrast to the well-documented protective actions of Sirt1, the role of endothelial Sirt2 remains unknown. Using cDNA microarray and PCR validation, we exam...

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Detalles Bibliográficos
Autores principales: Liu, Junni, Wu, Xiao, Wang, Xi, Zhang, Yun, Bu, Peili, Zhang, Qunye, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634502/
https://www.ncbi.nlm.nih.gov/pubmed/23478437
http://dx.doi.org/10.3390/ijms14035633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634502/
https://www.ncbi.nlm.nih.gov/pubmed/23478437
http://dx.doi.org/10.3390/ijms14035633

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