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Structure-Based Search for New Inhibitors of Cholinesterases

Cholinesterases are important biological targets responsible for regulation of cholinergic transmission, and their inhibitors are used for the treatment of Alzheimer’s disease. To design new cholinesterase inhibitors, of different structure-based design strategies was followed, including the modific...

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Detalles Bibliográficos
Autores principales: Bajda, Marek, Więckowska, Anna, Hebda, Michalina, Guzior, Natalia, Sotriffer, Christoph A., Malawska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634507/
https://www.ncbi.nlm.nih.gov/pubmed/23478436
http://dx.doi.org/10.3390/ijms14035608