Inhibition of Human Transthyretin Aggregation by Non-Steroidal Anti-Inflammatory Compounds: A Structural and Thermodynamic Analysis

Transthyretin (TTR) is a homotetrameric protein that circulates in plasma and cerebral spinal fluid (CSF) whose aggregation into amyloid fibrils has been associated with at least two different amyloid diseases: senile systemic amyloidosis (SSA) and familial amyloid polyneuropathy (FAP). In SSA aggre...

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Detalles Bibliográficos
Autores principales: Sant’Anna, Ricardo O., Braga, Carolina A., Polikarpov, Igor, Ventura, Salvador, Lima, Luis Mauricio T. R., Foguel, Debora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634512/
https://www.ncbi.nlm.nih.gov/pubmed/23466880
http://dx.doi.org/10.3390/ijms14035284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634512/
https://www.ncbi.nlm.nih.gov/pubmed/23466880
http://dx.doi.org/10.3390/ijms14035284

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