Control of RelB during dendritic cell activation integrates canonical and non-canonical NF-κB pathways

The NF-κB protein RelB controls dendritic cell (DC) maturation and may be targeted therapeutically to manipulate T cell responses in disease. Here we report that RelB promoted DC activation not as the expected RelB-p52 effector of the non-canonical NF-κB pathway, but as a RelB-p50 dimer regulated by...

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Detalles Bibliográficos
Autores principales: Shih, Vincent F.-S., Davis-Turak, Jeremy, Macal, Monica, Huang, Jenny Q., Ponomarenko, Julia, Kearns, Jeffrey D., Yu, Tony, Fagerlund, Riku, Asagiri, Masataka, Zuniga, Elina I., Hoffmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634611/
https://www.ncbi.nlm.nih.gov/pubmed/23086447
http://dx.doi.org/10.1038/ni.2446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634611/
https://www.ncbi.nlm.nih.gov/pubmed/23086447
http://dx.doi.org/10.1038/ni.2446

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