Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart

Endothelia in the atrioventricular (AV) canal of the developing heart undergo a prototypical epithelial mesenchymal transition (EMT) to begin heart valve formation. Using an in vitro invasion assay, an extracellular matrix protein, Olfactomedin-1 (OLFM1), was found to increase mesenchymal cell numbe...

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Detalles Bibliográficos
Autores principales: Lencinas, Alejandro, Chhun, Danny C., Dan, Kelvin P., Ross, Kristen D., Hoover, Elizabeth A., Antin, Parker B., Runyan, Raymond B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634647/
https://www.ncbi.nlm.nih.gov/pubmed/23264563
http://dx.doi.org/10.1242/dmm.010595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634647/
https://www.ncbi.nlm.nih.gov/pubmed/23264563
http://dx.doi.org/10.1242/dmm.010595

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