Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by complex neuronal and glial phenotypes. Recently, RNA-based mechanisms have been linked to ALS via RNA-binding proteins such as TDP-43, which has been studied in vivo using models ranging from yeast to rodents. We have developed...

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Detalles Bibliográficos
Autores principales: Estes, Patricia S., Daniel, Scott G., Mccallum, Abigail P., Boehringer, Ashley V., Sukhina, Alona S., Zwick, Rebecca A., Zarnescu, Daniela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634655/
https://www.ncbi.nlm.nih.gov/pubmed/23471911
http://dx.doi.org/10.1242/dmm.010710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634655/
https://www.ncbi.nlm.nih.gov/pubmed/23471911
http://dx.doi.org/10.1242/dmm.010710

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