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Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system
Toll-like receptors (TLRs) are an important class of pattern recognition receptors (PRRs) that recognize microbial and danger signals. Their downstream signaling upon ligand binding is vital for initiation of the innate immune response. In human and mammalian models, myeloid differentiation factor 8...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634667/ https://www.ncbi.nlm.nih.gov/pubmed/23471913 http://dx.doi.org/10.1242/dmm.010843 |