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A STAT3 Gene Expression Signature in Gliomas is Associated with a Poor Prognosis

Gliomas frequently display constitutive activation of the transcription factor STAT3, a protein that is known to be able to mediate neoplastic transformation. STAT3 regulates genes that play a central role in cellular survival, proliferation, self-renewal, and invasion, and a cohort of STAT3 target...

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Detalles Bibliográficos
Autores principales: Alvarez, James V., Mukherjee, Neelanjan, Chakravarti, Arnab, Robe, Pierre, Zhai, Gary, Chakladar, Abhijit, Loeffler, Jay, Black, Peter, Frank, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634710/
https://www.ncbi.nlm.nih.gov/pubmed/23641147