Cargando…
A STAT3 Gene Expression Signature in Gliomas is Associated with a Poor Prognosis
Gliomas frequently display constitutive activation of the transcription factor STAT3, a protein that is known to be able to mediate neoplastic transformation. STAT3 regulates genes that play a central role in cellular survival, proliferation, self-renewal, and invasion, and a cohort of STAT3 target...
Autores principales: | Alvarez, James V., Mukherjee, Neelanjan, Chakravarti, Arnab, Robe, Pierre, Zhai, Gary, Chakladar, Abhijit, Loeffler, Jay, Black, Peter, Frank, David A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634710/ https://www.ncbi.nlm.nih.gov/pubmed/23641147 |
Ejemplares similares
-
STAT5b is a marker of poor prognosis, rather than a therapeutic target in glioblastomas
por: Dubois, Nadège, et al.
Publicado: (2022) -
Epilepsy Associates with Decreased HIF-1α/STAT5b Signaling in Glioblastoma
por: Berendsen, Sharon, et al.
Publicado: (2019) -
A Novel 10-Gene Signature Predicts Poor Prognosis in Low Grade Glioma
por: Liu, Wentao, et al.
Publicado: (2021) -
High expression of stromal signatures correlated with macrophage infiltration, angiogenesis and poor prognosis in glioma microenvironment
por: Tian, Yixin, et al.
Publicado: (2020) -
TREM2 is associated with tumor immunity and implies poor prognosis in glioma
por: Yu, Mingchen, et al.
Publicado: (2023)