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T Follicular Helper Cells Mediate Expansion of Regulatory B Cells via IL-21 in Lupus-Prone MRL/lpr Mice

T follicular helper (Tfh) cells can mediate humoral immune responses and augment autoimmunity, whereas the role of Tfh cells on regulatory B (B10) cells in autoimmunity diseases is not clear. Here, we investigated the percentages of Tfh cells and B10 cells in lupus-prone MRL/Mp-lpr/lpr (MRL/lpr) mic...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Yang, Ji, Chu, Yiwei, Wang, Jiucun, Guan, Ming, Zhu, Xiaoxia, Xue, Yu, Zou, Hejian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634758/
https://www.ncbi.nlm.nih.gov/pubmed/23638156
http://dx.doi.org/10.1371/journal.pone.0062855