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Conserved N-Terminal Negative Charges Support Optimally Efficient N-type Inactivation of Kv1 Channels
N-type inactivation is produced by the binding of a potassium channel's N-terminus within the open pore, blocking conductance. Previous studies have found that introduction of negative charges into N-terminal inactivation domains disrupts inactivation; however, the Aplysia AKv1 N-type inactivat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634772/ https://www.ncbi.nlm.nih.gov/pubmed/23638135 http://dx.doi.org/10.1371/journal.pone.0062695 |