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Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells

Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ(9)-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, and c...

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Detalles Bibliográficos
Autores principales: Juknat, Ana, Pietr, Maciej, Kozela, Ewa, Rimmerman, Neta, Levy, Rivka, Gao, Fuying, Coppola, Giovanni, Geschwind, Daniel, Vogel, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634783/
https://www.ncbi.nlm.nih.gov/pubmed/23637839
http://dx.doi.org/10.1371/journal.pone.0061462