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Annexin Peptide Ac2-26 Suppresses TNFα-Induced Inflammatory Responses via Inhibition of Rac1-Dependent NADPH Oxidase in Human Endothelial Cells

The anti-inflammatory peptide annexin-1 binds to formyl peptide receptors (FPR) but little is known about its mechanism of action in the vasculature. Here we investigate the effect of annexin peptide Ac2-26 on NADPH oxidase activity induced by tumour necrosis factor alpha (TNFα) in human endothelial...

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Detalles Bibliográficos
Autores principales: Peshavariya, Hitesh M., Taylor, Caroline J., Goh, Celeste, Liu, Guei-Sheung, Jiang, Fan, Chan, Elsa C., Dusting, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634803/
https://www.ncbi.nlm.nih.gov/pubmed/23637767
http://dx.doi.org/10.1371/journal.pone.0060790