A Hypomorphic Lsd1 Allele Results in Heart Development Defects in Mice

Lysine-specific demethylase 1 (Lsd1/Aof2/Kdm1a), the first enzyme with specific lysine demethylase activity to be described, demethylates histone and non-histone proteins and is essential for mouse embryogenesis. Lsd1 interacts with numerous proteins through several different domains, most notably t...

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Detalles Bibliográficos
Autores principales: Nicholson, Thomas B., Singh, Anup K., Su, Hui, Hevi, Sarah, Wang, Jing, Bajko, Jeff, Li, Mei, Valdez, Reginald, Goetschkes, Margaret, Capodieci, Paola, Loureiro, Joseph, Cheng, Xiaodong, Li, En, Kinzel, Bernd, Labow, Mark, Chen, Taiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634827/
https://www.ncbi.nlm.nih.gov/pubmed/23637775
http://dx.doi.org/10.1371/journal.pone.0060913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634827/
https://www.ncbi.nlm.nih.gov/pubmed/23637775
http://dx.doi.org/10.1371/journal.pone.0060913

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