Reactive Oxygen Species-Activated Nanoprodrug of Ibuprofen for Targeting Traumatic Brain Injury in Mice

Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI recorded annually by the Centers for Disease Control. However, TBI has proven to be an extremely challenging condition to treat. Here, we apply a nanoprodrug strategy in a mouse model of TBI. The nov...

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Detalles Bibliográficos
Autores principales: Clond, Morgan A., Lee, Bong-Seop, Yu, Jeffrey J., Singer, Matthew B., Amano, Takayuki, Lamb, Alexander W., Drazin, Doniel, Kateb, Babak, Ley, Eric J., Yu, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634829/
https://www.ncbi.nlm.nih.gov/pubmed/23637912
http://dx.doi.org/10.1371/journal.pone.0061819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634829/
https://www.ncbi.nlm.nih.gov/pubmed/23637912
http://dx.doi.org/10.1371/journal.pone.0061819

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