Vanillin Inhibits Translation and Induces Messenger Ribonucleoprotein (mRNP) Granule Formation in Saccharomyces cerevisiae: Application and Validation of High-Content, Image-Based Profiling

Vanillin, generated by acid hydrolysis of lignocellulose, acts as a potent inhibitor of the growth of the yeast Saccharomyces cerevisiae. Here, we investigated the cellular processes affected by vanillin using high-content, image-based profiling. Among 4,718 non-essential yeast deletion mutants, the...

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Detalles Bibliográficos
Autores principales: Iwaki, Aya, Ohnuki, Shinsuke, Suga, Yohei, Izawa, Shingo, Ohya, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634847/
https://www.ncbi.nlm.nih.gov/pubmed/23637899
http://dx.doi.org/10.1371/journal.pone.0061748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634847/
https://www.ncbi.nlm.nih.gov/pubmed/23637899
http://dx.doi.org/10.1371/journal.pone.0061748

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