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Antagonism between FOXO and MYC Regulates Cellular Powerhouse

Alterations in cellular metabolism are a key feature of the transformed phenotype. Enhanced macromolecule synthesis is a prerequisite for rapid proliferation but may also contribute to induction of angiogenesis, metastasis formation, and tumor progression, thereby leading to a poorer clinical outcom...

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Detalles Bibliográficos
Autores principales: Peck, Barrie, Ferber, Emma C., Schulze, Almut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635031/
https://www.ncbi.nlm.nih.gov/pubmed/23630664
http://dx.doi.org/10.3389/fonc.2013.00096