Sirt6 regulates TNFα secretion via hydrolysis of long chain fatty acyl lysine

The Sir2 family of enzymes or sirtuins are known as nicotinamide adenine dinucleotide (NAD)-dependent deacetylases(1) and have been implicated in the regulation of transcription, genome stability, metabolism, and lifespan(2, 3). However, four of the seven mammalian sirtuins have very weak deacetylas...

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Detalles Bibliográficos
Autores principales: Jiang, Hong, Khan, Saba, Wang, Yi, Charron, Guillaume, He, Bin, Sebastian, Carlos, Du, Jintang, Kim, Ray, Ge, Eva, Mostoslavsky, Raul, Hang, Howard C., Hao, Quan, Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635073/
https://www.ncbi.nlm.nih.gov/pubmed/23552949
http://dx.doi.org/10.1038/nature12038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635073/
https://www.ncbi.nlm.nih.gov/pubmed/23552949
http://dx.doi.org/10.1038/nature12038

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