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Effects of Co-Administration of Intrathecal Nociceptin/Orphanin FQ and Opioid Antagonists on Formalin-Induced Pain in Rats
PURPOSE: Nociceptin/orphanin FQ (N/OFQ) as an endogeneous hexadecapeptide is known to exert antinociceptive effects spinally. The aims of this study were to demonstrate the antinociceptive effects of i.t. N/OFQ and to investigate the possible interaction between N/OFQ and endogenous opioid systems u...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Yonsei University College of Medicine
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635624/ https://www.ncbi.nlm.nih.gov/pubmed/23549827 http://dx.doi.org/10.3349/ymj.2013.54.3.763 |