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Cholesterol Depletion in Cell Membranes of Human Airway Epithelial Cells Suppresses MUC5AC Gene Expression

PURPOSE: If cholesterol in the cell membrane is depleted by treating cells with methyl-β-cyclodextrin (MβCD), the activities of transmembrane receptors are altered in a cell-specific and/or receptor-specific manner. The proinflammatory cytokines, IL-1β is potent inducers of MUC5AC mRNA and protein s...

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Detalles Bibliográficos
Autores principales: Song, Kee Jae, Kim, Na Hyun, Lee, Gi Bong, Kim, Ji Hoon, Kwon, Jin Ho, Kim, Kyung-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635649/
https://www.ncbi.nlm.nih.gov/pubmed/23549814
http://dx.doi.org/10.3349/ymj.2013.54.3.679