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Evaluation of Methylation Status in the 5'UTR Promoter Region of the DBC2 Gene as a Biomarker in Sporadic Breast Cancer

OBJECTIVE: Breast cancer is one of the most common malignancies in women worldwide. It is caused by a number of genetic and epigenetic factors. Aberrant hypermethylation of the promoter regions in specific genes is a key event in the formation and progression of breast cancers as well as the DBC2 ge...

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Detalles Bibliográficos
Autores principales: Hajikhan Mirzaei, Mehri, Noruzinia, Mehrdad, Karbassian, Hamid, Shafeghati, Yousef, Keyhanee, Mousa, Bidmeshki-Pour, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635816/
https://www.ncbi.nlm.nih.gov/pubmed/23626933