When the Most Potent Combination of Antibiotics Selects for the Greatest Bacterial Load: The Smile-Frown Transition

Conventional wisdom holds that the best way to treat infection with antibiotics is to ‘hit early and hit hard’. A favoured strategy is to deploy two antibiotics that produce a stronger effect in combination than if either drug were used alone. But are such synergistic combinations necessarily optima...

Descripción completa

Detalles Bibliográficos
Autores principales: Pena-Miller, Rafael, Laehnemann, David, Jansen, Gunther, Fuentes-Hernandez, Ayari, Rosenstiel, Philip, Schulenburg, Hinrich, Beardmore, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635860/
https://www.ncbi.nlm.nih.gov/pubmed/23630452
http://dx.doi.org/10.1371/journal.pbio.1001540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635860/
https://www.ncbi.nlm.nih.gov/pubmed/23630452
http://dx.doi.org/10.1371/journal.pbio.1001540

Ejemplares similares