PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance

Secretory vesicles in endocrine cells store hormones such as growth hormone (GH) and insulin before their release into the bloodstream. The molecular mechanisms governing budding of immature secretory vesicles from the trans-Golgi network (TGN) and their subsequent maturation remain unclear. Here, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Holst, Birgitte, Madsen, Kenneth L., Jansen, Anna M., Jin, Chunyu, Rickhag, Mattias, Lund, Viktor K., Jensen, Morten, Bhatia, Vikram, Sørensen, Gunnar, Madsen, Andreas N., Xue, Zhichao, Møller, Siri K., Woldbye, David, Qvortrup, Klaus, Huganir, Richard, Stamou, Dimitrios, Kjærulff, Ole, Gether, Ulrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635866/
https://www.ncbi.nlm.nih.gov/pubmed/23630454
http://dx.doi.org/10.1371/journal.pbio.1001542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635866/
https://www.ncbi.nlm.nih.gov/pubmed/23630454
http://dx.doi.org/10.1371/journal.pbio.1001542

Ejemplares similares