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The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosis from cynomolgus macaque infection

BACKGROUND: Mycobacterial interspersed repetitive units (MIRUs) are minisatellites within the Mycobacterium tuberculosis (Mtb) genome. Copy number variation (CNV) in MIRU loci is used for epidemiological typing, making the rate of variation important for tracking the transmission of Mtb strains. In...

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Detalles Bibliográficos
Autores principales: Ragheb, Mark N, Ford, Christopher B, Chase, Michael R, Lin, Philana Ling, Flynn, JoAnne L, Fortune, Sarah M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635867/
https://www.ncbi.nlm.nih.gov/pubmed/23496945
http://dx.doi.org/10.1186/1471-2164-14-145