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Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis
BACKGROUND: Fascin-1 is an actin-bundling protein expressed in many human carcinomas, although absent from most normal epithelia. Fascin-1 promotes filopodia formation, migration and invasion in carcinoma cells; in mouse xenograft tumor models it contributes to metastasis. Fascin-1 is an interesting...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635876/ https://www.ncbi.nlm.nih.gov/pubmed/23442983 http://dx.doi.org/10.1186/1741-7015-11-52 |