Copy-number variation of cancer-gene orthologs is sufficient to induce cancer-like symptoms in Saccharomyces cerevisiae

BACKGROUND: Copy-number variation (CNV), rather than complete loss of gene function, is increasingly implicated in human disease. Moreover, gene dosage is recognised as important in tumourigenesis, and there is an increasing realisation that CNVs may not be just symptomatic of the cancerous state bu...

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Detalles Bibliográficos
Autores principales: de Clare, Michaela, Oliver, Stephen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635878/
https://www.ncbi.nlm.nih.gov/pubmed/23531409
http://dx.doi.org/10.1186/1741-7007-11-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635878/
https://www.ncbi.nlm.nih.gov/pubmed/23531409
http://dx.doi.org/10.1186/1741-7007-11-24

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