Potentiation of in vitro and in vivo antitumor efficacy of doxorubicin by cyclin-dependent kinase inhibitor P276-00 in human non-small cell lung cancer cells

BACKGROUND: In the present study, we show that the combination of doxorubicin with the cyclin-dependent kinase inhibitor P276-00 was synergistic at suboptimal doses in the non-small cell lung carcinoma (NSCLC) cell lines and induces extensive apoptosis than either drug alone in H-460 human NSCLC cel...

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Detalles Bibliográficos
Autores principales: Rathos, Maggie J, Khanwalkar, Harshal, Joshi, Kavita, Manohar, Sonal M, Joshi, Kalpana S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635914/
https://www.ncbi.nlm.nih.gov/pubmed/23343191
http://dx.doi.org/10.1186/1471-2407-13-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635914/
https://www.ncbi.nlm.nih.gov/pubmed/23343191
http://dx.doi.org/10.1186/1471-2407-13-29

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