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Chapter 15: Disease Gene Prioritization

Disease-causing aberrations in the normal function of a gene define that gene as a disease gene. Proving a causal link between a gene and a disease experimentally is expensive and time-consuming. Comprehensive prioritization of candidate genes prior to experimental testing drastically reduces the as...

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Detalles Bibliográficos
Autor principal: Bromberg, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635969/
https://www.ncbi.nlm.nih.gov/pubmed/23633938
http://dx.doi.org/10.1371/journal.pcbi.1002902