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The Chlamydia pneumoniae Invasin Protein Pmp21 Recruits the EGF Receptor for Host Cell Entry

Infection of mammalian cells by the strictly intracellular pathogens Chlamydiae requires adhesion and internalization of the infectious Elementary Bodies (EBs). The components of the latter step were unknown. Here, we identify Chlamydia pneumoniae Pmp21 as an invasin and EGFR as its receptor. Modula...

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Detalles Bibliográficos
Autores principales: Mölleken, Katja, Becker, Elisabeth, Hegemann, Johannes H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635982/
https://www.ncbi.nlm.nih.gov/pubmed/23633955
http://dx.doi.org/10.1371/journal.ppat.1003325