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Distinct Types of Disorder in the Human Proteome: Functional Implications for Alternative Splicing

Intrinsically disordered regions have been associated with various cellular processes and are implicated in several human diseases, but their exact roles remain unclear. We previously defined two classes of conserved disordered regions in budding yeast, referred to as “flexible” and “constrained” co...

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Detalles Bibliográficos
Autores principales: Colak, Recep, Kim, TaeHyung, Michaut, Magali, Sun, Mark, Irimia, Manuel, Bellay, Jeremy, Myers, Chad L., Blencowe, Benjamin J., Kim, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635989/
https://www.ncbi.nlm.nih.gov/pubmed/23633940
http://dx.doi.org/10.1371/journal.pcbi.1003030