Structural mimicry between SLA/LP and Rickettsia surface antigens as a driver of autoimmune hepatitis: insights from an in silico study

BACKGROUND: Autoimmune hepatitis (AIH) is a chronic, progressive liver disease, characterized by continuing hepatocellular inflammation and necrosis. A subgroup of AIH patients presents specific autoantibodies to soluble liver antigen/liver-pancreas (SLA/LP) protein, which is regarded as a highly sp...

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Detalles Bibliográficos
Autores principales: Paiardini, Alessandro, Pascarella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636016/
https://www.ncbi.nlm.nih.gov/pubmed/23575112
http://dx.doi.org/10.1186/1742-4682-10-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636016/
https://www.ncbi.nlm.nih.gov/pubmed/23575112
http://dx.doi.org/10.1186/1742-4682-10-25

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