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Localization of Protein Aggregation in Escherichia coli Is Governed by Diffusion and Nucleoid Macromolecular Crowding Effect

Aggregates of misfolded proteins are a hallmark of many age-related diseases. Recently, they have been linked to aging of Escherichia coli (E. coli) where protein aggregates accumulate at the old pole region of the aging bacterium. Because of the potential of E. coli as a model organism, elucidating...

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Detalles Bibliográficos
Autores principales: Coquel, Anne-Sophie, Jacob, Jean-Pascal, Primet, Mael, Demarez, Alice, Dimiccoli, Mariella, Julou, Thomas, Moisan, Lionel, Lindner, Ariel B., Berry, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636022/
https://www.ncbi.nlm.nih.gov/pubmed/23633942
http://dx.doi.org/10.1371/journal.pcbi.1003038