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Localization of Protein Aggregation in Escherichia coli Is Governed by Diffusion and Nucleoid Macromolecular Crowding Effect
Aggregates of misfolded proteins are a hallmark of many age-related diseases. Recently, they have been linked to aging of Escherichia coli (E. coli) where protein aggregates accumulate at the old pole region of the aging bacterium. Because of the potential of E. coli as a model organism, elucidating...
Autores principales: | Coquel, Anne-Sophie, Jacob, Jean-Pascal, Primet, Mael, Demarez, Alice, Dimiccoli, Mariella, Julou, Thomas, Moisan, Lionel, Lindner, Ariel B., Berry, Hugues |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636022/ https://www.ncbi.nlm.nih.gov/pubmed/23633942 http://dx.doi.org/10.1371/journal.pcbi.1003038 |
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