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Analysis of Human Protein Replacement Stable Cell Lines Established using snoMEN-PR Vector

The study of the function of many human proteins is often hampered by technical limitations, such as cytotoxicity and phenotypes that result from overexpression of the protein of interest together with the endogenous version. Here we present the snoMEN (snoRNA Modulator of gene ExpressioN) vector te...

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Detalles Bibliográficos
Autores principales: Ono, Motoharu, Yamada, Kayo, Endo, Akinori, Avolio, Fabio, Lamond, Angus I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636044/
https://www.ncbi.nlm.nih.gov/pubmed/23638031
http://dx.doi.org/10.1371/journal.pone.0062305