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Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Africa

BACKGROUND: Malaria in pregnancy is one of the most common preventable causes of maternal and neonatal morbidity and mortality in sub-Saharan Africa. To prevent its adverse effects, such as maternal anaemia, placental parasitaemia and low birth weight (LBW) neonates, the World Health Organization re...

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Detalles Bibliográficos
Autores principales: Chandra, Richa S, Orazem, John, Ubben, David, Duparc, Stephan, Robbins, Jeffery, Vandenbroucke, Pol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636121/
https://www.ncbi.nlm.nih.gov/pubmed/23577619
http://dx.doi.org/10.1186/1475-2875-12-122