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Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Africa
BACKGROUND: Malaria in pregnancy is one of the most common preventable causes of maternal and neonatal morbidity and mortality in sub-Saharan Africa. To prevent its adverse effects, such as maternal anaemia, placental parasitaemia and low birth weight (LBW) neonates, the World Health Organization re...
Autori principali: | , , , , , |
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Natura: | Online Articolo testo |
Lingua: | English |
Pubblicazione: |
BioMed Central
2013
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Soggetti: | |
Accesso online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636121/ https://www.ncbi.nlm.nih.gov/pubmed/23577619 http://dx.doi.org/10.1186/1475-2875-12-122 |