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Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-α
BACKGROUND: Tumor necrosis factor-alpha (TNF-α) is elevated early in injured brain after traumatic brain injury (TBI), in humans and in animals. Etanercept (a TNF-α antagonist with anti-inflammatory effects) attenuates TBI in rats by reducing both microglial and astrocytic activation and increased s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636122/ https://www.ncbi.nlm.nih.gov/pubmed/23496862 http://dx.doi.org/10.1186/1471-2202-14-33 |