Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ

We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo. Here we interrogated the mechanism by which these novel compounds activate AMPK, a leadi...

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Detalles Bibliográficos
Autores principales: Iseli, Tristan J., Turner, Nigel, Zeng, Xiao-Yi, Cooney, Gregory J., Kraegen, Edward W., Yao, Sheng, Ye, Yang, James, David E., Ye, Ji-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636144/
https://www.ncbi.nlm.nih.gov/pubmed/23638033
http://dx.doi.org/10.1371/journal.pone.0062309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636144/
https://www.ncbi.nlm.nih.gov/pubmed/23638033
http://dx.doi.org/10.1371/journal.pone.0062309

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