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High-Resolution Mapping of H1 Linker Histone Variants in Embryonic Stem Cells

H1 linker histones facilitate higher-order chromatin folding and are essential for mammalian development. To achieve high-resolution mapping of H1 variants H1d and H1c in embryonic stem cells (ESCs), we have established a knock-in system and shown that the N-terminally tagged H1 proteins are functio...

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Detalles Bibliográficos
Autores principales: Cao, Kaixiang, Lailler, Nathalie, Zhang, Yunzhe, Kumar, Ashwath, Uppal, Karan, Liu, Zheng, Lee, Eva K., Wu, Hongwei, Medrzycki, Magdalena, Pan, Chenyi, Ho, Po-Yi, Cooper, Guy P., Dong, Xiao, Bock, Christoph, Bouhassira, Eric E., Fan, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636266/
https://www.ncbi.nlm.nih.gov/pubmed/23633960
http://dx.doi.org/10.1371/journal.pgen.1003417