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Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome

Brain aging frequently underlies cognitive decline and is a major risk factor for neurodegenerative conditions. The exact molecular mechanisms underlying brain aging, however, remain unknown. Whole transcriptome sequencing provides unparalleled depth and sensitivity in gene expression profiling. It...

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Detalles Bibliográficos
Autores principales: Wood, Shona H., Craig, Thomas, Li, Yang, Merry, Brian, de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636386/
https://www.ncbi.nlm.nih.gov/pubmed/22555619
http://dx.doi.org/10.1007/s11357-012-9410-1