Virtual screening for oseltamivir-resistant a (H5N1) influenza neuraminidase from traditional Chinese medicine database: a combined molecular docking with molecular dynamics approach

The neuraminidase (NA) of the influenza virus is the target of antiviral drug, oseltamivir. Recently, cases are reported that Influenza virus becoming resistant to oseltamivir, necessitating the development of new long-acting antiviral compounds. Most importantly, H274Y mutation in neuraminidase exh...

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Detalles Bibliográficos
Autores principales: Karthick, Vasudevan, Ramanathan, Karuppasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636431/
https://www.ncbi.nlm.nih.gov/pubmed/23638404
http://dx.doi.org/10.1186/2193-1801-2-115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636431/
https://www.ncbi.nlm.nih.gov/pubmed/23638404
http://dx.doi.org/10.1186/2193-1801-2-115

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